Dismissed as “biased” and low-quality just a decade ago, real-world data now shines thanks to AI-enhanced curation. The discussants explain how contemporary RWE validates trial outcomes across messy geographies and comorbidity spectra, tempering the “ideal-patient” and “selection-bias” critique that shadows top-line releases. The future, they opine, pairs pivotal trials with machine-harvested reality checks in near real time.
